DIYgenomics - Synbio self-tests
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A significant barrier to the wide-scale adoption of citizen science in the context of health self-management, intervention exploration, and preventive medicine implementation is the high cost, inconvenience and discomfort involved in obtaining traditional lab tests. While many may be ordered in a direct-to-consumer fashion through DirectLabs, the Life Extension Foundation, and other websites, it still costs ~$100 per test.
The challenge is to identify the requisite chemistry and processes involved and see if it may be possible to make simple consumer-friendly finger-stick blood test cartridges, similar to the glucose and HDL measurement kits sold at drug stores, which self-experimenters may perform at home or at community biolabs. Continuous monitoring via microneedle arrays would be useful for self-tracking of glucose levels and other measures. DIYgenomics has a pending grant application with the Immortality Institute to fund a Cholestech LDX lipid measurement device via finger-stick cartridge at a silicon valley-based biolab. Next-gen synbio companies such as Biodesic may be able to look at the feasibility of developing such tests.
Top 20 Wish List of basic tests for delivery as a one-off or comprehensive panel:
Traditional Blood markers:
- Cholesterol - HDL
- Cholesterol - LDL
- Cholesterol - Triglycerides
- Homocysteine
- Vitamin B-12
- Folate
- Vitamin D
- Creatinine
- eGFR
- Cortisol
- Calcium
- Iron
- Aldosterone
Hormones
- Estrogen
- Progesterone
- Testosterone
- Estradiol
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